News
Natural plant extract boosts roundworm lifespan by 40%

Researchers at Louisiana State University (LSU) may have uncovered the key to living a longer and healthier life – thanks to the humble roundworm.
The researchers fed the worms various doses of Artemisia scoparia – a natural plant extract native to Asia.
Worms treated with the highest and second highest doses showed a near-immediate improvement to metabolic health.
They also lived 40 per cent longer and handled stress better than the control group.
The research also revealed that Artemisia scoparia helps convert the body’s unhealthy fat stores into healthy fat stores.
The study builds on previous work on metabolic health in mice, leading the researchers to conclude that the results could be replicated in humans.
Bhaswati Ghosh, LSU student and lead author of the published study, said:
“Until recently, it wasn’t really known how ageing could be modified through diet, or how core metabolic signalling pathways influence longevity.
“What we’ve been able to show is that a natural extract can come in and influence these pathways in much the same way a genetic mutation would.
“Importantly, it gives us a therapeutic standpoint.
“We know age is the primary risk factor for many diseases, such as cancer and cardiovascular disease, but if you think of ageing as a treatable disease, you can actually treat many diseases at once.”
The greatest longevity in lifespan was seen in the worms treated during the time they reached reproductive maturity.
However, even in the worms treated during middle-age, Artemisia scoparia increased lifespan by 20 per cent.
As well as exploring the life-prolonging potential of the plant, the research reinforces the link between metabolic health, fat regulation and longer lifespans.
The worms with the increased lifespan grew fatter and slower but at the same time, healthier and more resilient.
Bohnert said:
“Usually people think of fat as ‘bad,’ but in these cases, it seems good, and actually pro-longevity.
“Artemisia scoparia could have some exciting potential as a dietary supplement.
“Also, the simple fact that an organism is short, fat and slow-moving does not necessarily qualify it as in poor health.
“These phenotypes must be considered in the full context of other parameters, including lifespan.”
Header Image Courtesy of Bhaswati Ghosh, LSU
News
Gut-friendly foods may damage heart, charity warns
News
Diabetes patients face increased risk of undiagnosed heart failure

People with diabetes may have undiagnosed heart failure that could be detected by a simple screening blood test, research suggests.
The TARTAN-HF trial found that one in four patients with diabetes who had at least one other risk factor for heart failure had undiagnosed heart failure detected through screening with a blood test and ultrasound scanning of the heart.
Experts said the findings show the extent of unrecognised heart failure in people with diabetes, and how the condition can be detected using a widely available blood test called NT-proBNP, which measures how much strain the heart is under.
They suggest a heart failure screening programme for diabetics could improve diagnosis rates, lead to earlier treatment and potentially reduce the risk of hospitalisation and death.
The study, involving 700 patients, was led by the University of Glasgow in collaboration with AstraZeneca, Roche Diagnostics, Us2.ai, NHS Greater Glasgow and Clyde and NHS Lanarkshire.
Dr Kieran Docherty, clinical senior lecturer at the University of Glasgow’s School of Cardiovascular and Metabolic Health, said: “Our results from the landmark TARTAN-HF trial identified heart failure in a large proportion of people living with diabetes, emphasising the need for a heart failure screening strategy in this group of patients.
“We know that many of the symptoms and signs of heart failure are non-specific, and may go unrecognised as potentially being due to heart failure for a long time.
“The strategy used in our trial is simple and easy to implement in clinical practice, and will aid in the early identification of heart failure in people with diabetes, and facilitate the initiation of medications that we know improve outcomes in patients with heart failure.”
The study, which began more than three years ago, involved more than 700 people with diabetes from the two health board areas who had at least one other risk factor for heart failure.
They were randomly assigned either to receive heart failure screening or to continue with their usual care.
Researchers found screening uncovered a large number of previously unrecognised cases of heart failure. Around one in four, or 24.9 per cent, of those screened were found to have the condition within six months, compared with 1 per cent in the group continuing their usual care.
The study, involving patients with type 1 and type 2 diabetes, found almost all of the participants found to have heart failure had preserved ejection fraction, which can be difficult to detect without dedicated testing.
The findings of the TARTAN-HF trial were presented at the American College of Cardiology conference taking place from 28 to 30 March in New Orleans in the US.
Dr Edward Piper, medical director at AstraZeneca UK, said: “Delayed diagnosis and treatment of heart failure in people with type 2 diabetes contributes to poor long-term outcomes. TARTAN-HF demonstrates that targeted, risk-based screening can identify previously undiagnosed heart failure in approximately one in four high-risk patients with diabetes, enabling earlier intervention with guideline-directed therapy.”
Dr Christian Simon, head of global medical affairs at Roche Diagnostics, said: “We are proud to have supported the landmark TARTAN-HF trial. These findings demonstrate the transformative power of early, accessible diagnostics like the NT-proBNP blood test.
“By identifying unrecognised heart failure in people with diabetes, we enable clinicians to initiate appropriate treatments sooner, ultimately improving patient outcomes and lives.”
News
UK government announces £6.3m fund to boost men’s health

The UK has launched a £6.3m men’s health fund to back local projects aimed at helping men and boys live longer, healthier lives.
The Men’s Health Community Fund is a partnership between the Department of Health and Social Care, Movember and People’s Health Trust.
The government is contributing £3m, while the two charities are more than doubling that to take the total to £6.3m.
Grants will support community projects reaching underserved men and boys aged 16 and over, particularly in the most disadvantaged areas and at key points in their lives such as becoming a father, losing a job or retiring.
Projects could include support for new fathers, activities for men facing loneliness and social isolation, services to help young men engage with the health system, and support for men in work, out of work and moving into retirement.
The programme will bring together voluntary, community and social enterprise organisations to test new ways of reaching men who are least likely to use traditional health services.
An evaluation funded through the National Institute for Health and Care Research will assess what works and help inform future policy and delivery.
Health and social care secretary Wes Streeting said: “Too many men across the country are living shorter, less healthy lives, particularly those in our most disadvantaged communities.
“This new partnership will help men get the support they need in the places they feel most comfortable, their communities, among people they trust.
“By working with expert charities and local organisations, we can reach the men who are too often missed by traditional services and help them take better care of their mental and physical health.”
“It is a key step in delivering our first ever Men’s Health Strategy and driving forward our ambition to halve the gap in healthy life expectancy between the richest and poorest areas.”
The Men’s Health Strategy sets out plans to tackle the physical and mental health challenges men and boys face.
Men can be less likely to seek help and more likely to suffer in silence, while higher rates of smoking, drinking, gambling and drug use are damaging men’s health and affecting families, workplaces and communities.
The government is also investing £3.6m over the next three years in suicide prevention projects for middle-aged men in local communities across areas of England where men are most at risk, many of which are also among the most deprived. Suicide is one of the biggest killers of men under 50, and three-quarters of all suicides are men.
The projects will aim to break down barriers middle-aged men face in seeking support, including stigma around asking for help and a lack of awareness of what is available and how to access it.
They will be co-designed with experts and men with lived experience of mental health crises and suicidal thoughts.
News4 weeks agoCentenarian study probes healthy ageing
News4 weeks agoActive sitting linked to lower dementia risk
News4 weeks agoEndogenex raises US$50m for diabetes procedure
News4 weeks agoWorking nights undermines type 2 diabetes management – study
News4 weeks agoUK government announces £6.3m fund to boost men’s health
News4 weeks agoBrain health collaboratory launches in Gulf South
Wellness4 weeks agoSocial isolation is a horrible consequence of dementia – AI could be an answer
News3 weeks agoDiabetes patients face increased risk of undiagnosed heart failure

















