Mobility
Managing knee osteoarthrisis to live better every day

By Ganit Segal, MPE, MBA, EVP — Chief Scientific & Innovation Officer of AposHealth
According to the World Health Organization (WHO), 365 million people live with knee osteoarthritis (OA), a condition that causes chronic pain and impairs mobility.
While there are treatments that people can use to manage their pain, many have limitations that impede their effectiveness.
Understanding the options available is essential for those seeking to live more efficiently with OA.
OA has more effects than just the nuisance of pain. A failure to address OA pain appropriately can have significant impacts on a person’s physical and mental health.
For example, someone who becomes sedentary to avoid their pain may lose the health benefits of a physically active lifestyle, while those who disrupt their regular activities due to their pain may suffer from isolation and mental health problems.
Pharmaceutical treatment for OA
As is often the case with painful conditions, the immediate instinct for treating OA-related pain is medication.
However, one must remember that OA is a common condition that will affect a patient for the rest of their life.
Solutions like pain medication simply mask the symptoms of OA temporarily, failing to address the reason why patients are suffering pain.
NSAIDs (non-steroidal anti-inflammatory drugs) are common in the management of OA for many people.
Unfortunately, NSAIDs have some side effects, such as gastrointestinal issues, cardiovascular risks, and kidney damage. As a result, they aren’t a long-term solution for OA pain management.
In more severe cases, patients may turn to prescription medications, such as opioids.
While these medications can be very effective at relieving pain temporarily, they do not help improve joint function or mobility.
Beyond that, they also come with a high risk of dependency and addiction. Because of this, most patients should avoid using opioids to manage their OA pain.
Another common treatment for OA pain is corticosteroid injections, which can provide temporary relief and improve mobility on a short-term basis.
However, studies have shown that corticosteroid shots contribute to disease progression and are currently conditionally recommended by the societies in the care-management guidelines and only after discussing the option with a physician and understanding the risks.
Over time, this can accelerate joint deterioration, meaning that, like other pharmaceutical treatments, they are not a sustainable strategy.
These risks and limitations of medications make it evident that they are not viable, long-term solutions for the pain of knee osteoarthritis.
Non-invasive solutions are a critical alternative for patients, whether they cannot safely take pain medications for an extended period of time or otherwise cannot risk the consequences of this approach.
Non-pharmaceutical treatments for OA
In the early stages of an OA diagnosis, some people may turn to bracing and orthotics to ease their symptoms and help restore mobility.
By redistributing forces on the knee and providing key joint support, bracing and orthotics can temporarily relieve pain and allow people to resume more of their normal daily activities.
However, because these devices do not address the root cause of the condition, they may cause the patient to become reliant on them.
Some people may turn to assistive devices like canes or walkers for support, which can be instrumental in helping patients with OA maintain their mobility despite their condition.
They also serve as important safety devices, as they can reduce the risk of falling due to instability.
However, since they do not improve function or gait in the long term, they will not contribute to any improvement and are often a sign of the disease progressing.
The key similarity between these treatments is that they address movement efficiency, but do not address the root cause of the pain.
The most effective solution would be one that addresses the cause, as this will allow them to manage their pain more effectively over time.
One of the leading causes of OA pain is a patient’s gait — their way of walking.
When a joint is painful, the body naturally compensates by altering how it moves.
This leads to unbalanced muscle use, joint misalignment, and additional strain on surrounding areas like the lower back, hips, and knees.
To improve long-term outcomes, people with OA need biomechanical and neuromuscular retraining to restore proper movement patterns, reduce joint stress, and improve function.
Thankfully, wearable medical devices are available that patients can use to improve their gait patterns and retrain neuromuscular function, which can improve mobility and reduce pain.
These devices can also be used from the comfort and convenience of one’s own home since they can be worn for just two hours a day as people go about their daily routine.
However, it is important to note that the efficacy of these solutions depends on adherence and proper use by the patient.
That said, if patients use biomechanical and neuromuscular retraining devices according to their specifications, they can benefit from the increased mobility and pain relief those devices provide.
Although OA is a common condition, that does not mean that people should have to allow it to interfere with their daily lives.
They may just need a non-surgical solution to live their life on their own terms.
Ganit Segal holds an MBA and a master’s degree in life science, with a specialisation in biomechanics and has more than 15 years’ experience in medical research including various clinical trial methodologies, scientific publications with over 35 publications in peer-review journals and substantial experience in scientific reviews including global clinical trends and guidelines, comparative analysis and more.
Since 2017, Ganit began laying the company’s foundations to collect and analyze big data in order to support post-marketing clinical activity and ongoing account management and improve patient care.
News
Captioning glasses win AARP pitch at CES

Captify won AARP’s AgeTech pitch at CES, taking US$10,000 for captioning glasses that show real-time subtitles for people with hearing loss.
San Francisco-based Captify beat four other AgeTech firms at the 2026 AgeTech After Dark event.
The glasses show captions in the wearer’s field of view and are claimed to be 98 per cent accurate, including in noisy settings.
The frames resemble standard eyewear and cost US$499 or US$799 depending on the model.
An optional US$15 monthly subscription offers AI-generated conversation summaries and other features. Captions can be translated into more than 70 languages.
The AgeTech Collaborative from AARP, which backs technologies to help adults age well, has hosted pitch competitions since 2015.
Other start-ups featured were Accelera, which makes wearable bands using gentle vibrations to improve balance and help prevent falls; ATDev, developing personal robotics for people with mobility impairments; Kinemo Proprio, enabling hands-free control of digital devices via body gestures; and Memcara, using music therapy to help people with dementia communicate.
Memcara co-founder Christina Tadin, a board-certified music therapist, said: “Even as memory fades, the capacity to communicate, feel and express identity remains far more intact than most people realise.
“What is missing is the infrastructure to support what remains.”
Wellness
Cycling may lower dementia risk, study finds

Cycling instead of driving or taking public transport is linked to a 19 per cent lower risk of developing dementia.
An analysis of nearly 480,000 people in Great Britain also found regular cyclists had a 22 per cent lower risk of Alzheimer’s disease compared with those using cars, buses or trains.
More than 55m people worldwide currently live with dementia, with numbers predicted to almost triple by 2050.
Physical activity has been identified as one of 14 factors that could prevent or delay about 45 per cent of cases.
Researchers from the UK Biobank study tracked the health of more than 500,000 people aged 40 to 69, recruited between 2006 and 2010.
Participants, who were aged 56.5 on average, answered questionnaires about which transport modes they used most often for non-work journeys.
Over a median follow-up of 13.1 years, 8,845 developed dementia and 3,956 developed Alzheimer’s disease.
The study examined nonactive travel (car, bus, train), walking, mixed walking (walking with nonactive modes), cycling, and mixed cycling (cycling with other modes).
Brain scans showed that cycling and mixed cycling were most strongly linked to greater hippocampal volumes.
The hippocampus is the part of the brain responsible for memory and learning.
Walking and mixed walking were associated with a 6 per cent lower dementia risk but, unexpectedly, a 14 per cent higher Alzheimer’s risk.
Dr Joe Verghese, professor and chair of neurology at Stony Brook University in New York, who was not involved in the study, said: “This study is the first to show that cycling is linked not only to a lower risk of dementia but also to a larger hippocampus.”
The APOE ε4 gene, the strongest genetic risk factor for Alzheimer’s, also influenced outcomes.
Participants without this gene variant had a 26 per cent lower dementia risk, while carriers had a 12 per cent lower risk.
“Travel modes were self-reported at a single time point, so we don’t know how people’s habits changed over time,” said Dr Sanjula Singh, instructor of neurology at Harvard Medical School.
Singh was not involved in the study.
“Most participants were White and healthier at baseline, so the results may not apply to all communities.
“And, most importantly, as this is an observational study, it cannot prove that cycling directly prevents dementia.
“It only shows an association.”
Older adults who cycle regularly are likely a healthier subgroup, and cycling may also reflect favourable genetics, with risk lowest among those without genetic susceptibility, Verghese said.
Participants choosing active travel were more often women, nonsmokers, more educated, more physically active overall, with lower body mass index and fewer chronic conditions.
Those in the cycling groups were more often men with healthier lifestyles.
The higher Alzheimer’s risk linked with walking could reflect participants already having balance or driving issues, said Dr Glen Finney, behavioural neurologist and director of the Memory and Cognition Program at Geisinger Health System in Pennsylvania.
Walking pace matters too, Finney added. Leisurely walking, especially for short distances, may not give the same benefit as brisker, longer walks.
The study did not report frequency, pace or duration of walking or cycling.
News
Jumping could be key to healthy ageing, study finds

Jumping may help protect ageing bones and cut fracture risks, with research showing short daily routines can strengthen bone density in adults.
High-impact exercise strengthens bones, which weaken as the body’s rate of bone formation slows with age.
Regular jumping can raise bone density – the level of calcium and other minerals that indicates bone strength and fracture risk.
A study involving 60 women aged 25 to 50 found that doing ten high-impact jumps twice a day for four months increased hip bone density.
Dr Larry Tucker, a professor at Brigham Young University, said: “Our study showed significant benefits over time.
“Women have to do the jumps daily to get the benefits. In addition, keep in mind, as women age it’s more and more difficult to improve bone density.”
Women are particularly at risk as they lose bone mass earlier and faster than men, having smaller, thinner bones.
The hormone oestrogen, which falls sharply after menopause, accelerates this decline, according to the Bone Health & Osteoporosis Foundation.
That raises the likelihood of osteoporosis – a disease where bones become fragile enough to fracture from minor knocks or even a cough.
About 10m people in the US live with the condition, more than 8m of them women.
Bone loss, however, affects both sexes, with 44m Americans having low bone density, according to the American Medical Association. Genetics and other health issues also influence how quickly bones weaken.
Lifestyle is described as “pivotal” for bone health by The Ohio State University.
Dr Jackie Buell, a sports dietitian there, highlighted the value of varied nutrition and strength training.
She said: “The nature of the exercise you want to do to help your bones is something that loads the bone, like jumping for the hips or push-ups for the wrists.”
Daily training is not essential. A few dozen jumps done twice weekly could “go a long way in benefiting your bone health throughout your lifespan,” said Pam Bruzina, a professor of nutrition and exercise physiology at the University of Missouri.
Improvements to bone density may be seen in as little as six months. Benefits are seen in younger and older adults, though most people reach peak bone mass in their early thirties.
Some caution is needed. Without sufficient muscle strength or if joint pain is present, jumping may risk injury.
Experts advise people with osteoporosis not to jump unsupervised because of the chance of fractures. Several months of resistance training around the hips and spine can help reduce risks.
Not all jumps are equally effective. Options such as explosive back-and-forth or side-to-side movements, or box jumps, bring the most benefit. Jumping rope is less useful, as bone growth depends on maximising landing impact and skeletal stress.
“Any intervention that slows that loss or mitigates it is better than nothing,” said Jocelyn Wittstein, an associate professor of orthopaedic surgery at Duke University School of Medicine.
“Any load-bearing activity on your legs is better than being sedentary.”
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